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The Netherlands Epidemiology of Obesity (NEO) Study Database and Biobank

Technology Overview

Interested in conducting research on obesity and metabolic disease?

Leiden University Medical Center Netherlands has finished enrollment of the Epidemiology of Obesity Study (NEO). Information from 6,000 obese participants from the Netherlands was gathered over a four-year period with a goal of aiding researchers in their pursuit of causes and treatments for obesity and metabolic disease. Information ranging from health and depression questionnaires to heart and brain MRIs has been collected from 6,000 participants with a BMI = 27 kg/m2 or higher and 1,000 participants with a BMI < 27 kg/m2. Endpoints include diagnosis of Type 2 diabetes, cardiovascular disease, COPD, asthma, chronic kidney disease, osteoarthritis and all-cause mortality. Analyses were conducted on blood, serum, urine and plasma. Serum, DNA, RNA have been saved for future studies.

Details and State of Development:

Four-year enrollment period is complete; follow-up is on-going.


Collaborative studies on the effect of obesity on disease Access to data and samples for in-depth studies.


The database/biobank is now open for access. LUMC investigators involved in the NEO Study are also interested in research collaborations using the database/biobank.

Keywords: obesity, metabolomic disease, biobank


Key benefits

  • Information gathered includes 10 questionnaires, > 6,000 participants
  • Data was gathered to assess cardiac, pulmonary, metabolic, kidney and bone disease

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